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模式生物研究

斑马鱼分析分选系统

时间:2016-09-29来源:本站作者:玉研仪器

详细介绍

  The COPAS platform is designed for the measurement of objects ranging in size from 20–1500 microns (diameter). Each COPAS model features a specially engineered fluidic path, flow cell and optics optimized for a specific subset of that size range to provide maximum speed, accuracy, resolution and throughput, depending on the application. Instruments can dispense objects either into bulk receptacles or multi-well plates.

 

  Applications:

 

  For automated rapid analysis, sorting and dispensing of 20-1,500 micron objects …

  Small Animal Models (base business)

  – nematode worms, fruit flies,zebrafish, mosquitoes, sea urchins, Daphnia, ….

  “Beads” & “Seeds”

  Large cells / cell clusters(new)

  –stem cells / embryoid bodies

  –Pancreatic islets

  –Adipocytes, hepatocytes, duct cells

  Others:

  >1,000 model organism papers

  Insights into human diseases

  –Alzheimer's, Parkinson's, aging, cholesterol metabolism, diabetes, obesity . . . .

  Genes tagged w/ fluorescent markers(indicate if a gene is turned on/off)

  Sort 15-50 events / second

  Gentle -- Dispensed organisms are unharmed, viable, and sterile environment is maintained

 

    斑马鱼分析分选系统的产品特点:

 

  · 目前市面上唯一能够分选10-1500um生物微粒的自动化高通量分选系统;

  (COPAS Platform:20-1500um;BioSorter Platform:10-1500um )

  · 模式动物、模式植物种子与花粉、大体积细胞与细胞簇、微球/颗粒、高通量药物分选;

  · 同时检测微粒的五种光学参数:微粒的尺寸、光密度及三色荧光信号;

  · 专利的气流分选装置,保证收集到的生物活体或敏感化学物质的活性和完整性,整个过程对微粒的生物活性不会产生任何负面影响;

  · 运用于On-bead assays中,筛选速度达到每小时100,000个化合物,同时大大节省样品的消耗量。

 


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