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悬浮细胞分析系统是爱尔兰cellix公司推出的用于研究细胞-细胞,细胞-分子之间相互作用的系统。该系统为细胞研究提供了具有生理相关性的流体剪切力,用于细胞粘附、迁移、趋化性研究等方面。
The VenaFluxTM Platform is the first semi-automated microfluidic platform capable of executing cell rolling, binding/adhesion and migration studies under shear flow mimickingin vivo flow rates. For higher throughput requirements of cell-based assays under shear flow, the VenaFluxTM Platform will meet your needs.
Ideal for:
Ø Functional cell-ligand and cell-cell interaction studies.
Ø Morphologhy analysis of cell adhesion and migration.
Ø Tracking of flowing, rolling and migrating cells.
Ø IC50 curves easily produced.
Ø Preclinical drug development and lead optimization.
Benefits:
Ø Robust and easy to use.
Ø Ideal for use with whole blood for platelet adhesion, aggregation and thrombi formation (thrombosis); bio-film culture over extended periods of time.
Ø Easy to study cell adhesion, migration and transmigration - more physiologically relevant than static assays!
VenaFluxTM Robotic Sample Handling96-well plate integration
微流体技术与传统静态方式实验结果对比:
Platelet adhesion on vWF in static conditionsPlatelet adhesion on vWF under flow conditions at a shear stess of 60 dyne/cm2
Human endothelial cell culture in static conditionsHuman endothelial cell culture under flow conditions at a shear stess of 10 dyne/cm2
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