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疼痛与炎症研究

双足平衡测痛仪

时间:2016-09-17来源:本站作者:玉研仪器

详细介绍

双足平衡测痛仪(双足平衡测试,Incapacitance Analgesia TestIncapacitance Meter Tester Mice, Rats and Birds测试评估大鼠或小鼠后肢的痛觉和发炎,测量精准,更多详情敬请来电咨询)

 

双足平衡法测痛仪用于对大鼠或小鼠后肢的痛觉和发炎测试评估,克服了其它测试方式可能引起的动物紧张或主观性问题,该技术采用双通道重量平均法,可以同时对一只动物进行控制和测试,可选购大鼠或小鼠两种型号。

 

双足平衡测试法(Incapacitance Analgesia Meter)可以自动并且是可重复的评估止痛效果。它可测量体重在小动物后肢分配情况,每个肢体对感应器施加的力量,在选定的时间周期内的平均值,可以表现受试对象从一边到另一边的抬起足部,因此可以提供量化的体重在后肢的平衡分配。

 

Incapacitance Test Meter is used for test assessment of pain and or inflammation of the hind limbs on mice and rats. It overcomes the drawbacks of other methods that might cause unnececessary stress or subjectivity on the animal. The technique known as dynamic weight bearing enables the test on both limbs allowing a clean stress free correlation to the paw pressure test. Control and testing can be done on the same animal at the same time.

 

Animals are placed in the supplied rodent restrainers. Hind limbs rest on the two weight averaging platform pads. As the animal shifts their weight from each pad, the unit records the average weight in grams over a selectable test period of 5 to 999 seconds. Alphanumeric readout displays the weight of both limbs and testing start and stop features. These features are controlled on the front panel: Start, stop, reset.

 

双足平衡法测痛仪主要特点: 

 

Ø Mice, Rats, and Birds

Ø Precise programmable digital control 

Ø Reaction is detected automatically 

Ø Manual override of all timer functions 

Ø Alphanumeric readout 

Ø All Functions and parameters entered via key-pad 

Ø Footswitch - RS232

Ø Software - USB (optional)

 

部分参考文献:

Evaluation of liposome-encapsulated butorphanol tartrate for alleviation of experimentally induced arthritic pain in green-cheeked conures (Pyrrhura molinae)

JR Paul-Murphy, LA Krugner-Higby… - American journal of …, 2009 - Am Vet Med Assoc

... f. Paralube, Fougera, Melville, NY. g. IITC model 600 incapacitance meterIITC Life
Science, Woodland, Calif. h. Canon Optura 40, Canon USA Inc, Lake Success, NY. i.
Windows Movie Maker, version 2.1, Microsoft Corp, Redmond, Wash. ...

 

[HTML] Hyperalgesia, synovitis and multiple biomarkers of inflammation are suppressed by interleukin 1 inhibition in a novel animal model of gouty arthritis

R Torres, L MacDonald, SD Croll, J Reinhardt… - Annals of the …, 2009 - ard.bmj.com

... The results are presented as the percentage change from the baseline readings. To test
willingness to bear weight on injected ankles, the weightbearing test was performed using an
Incapacitance meter (model 600IITC Life Sciences, Woodland Hills, California, USA). ...

 

Analgesic effects of carprofen and liposome-encapsulated butorphanol tartrate in Hispaniolan parrots (Amazona ventralis) with experimentally induced arthritis

JR Paul-Murphy, KK Sladky… - American journal of …, 2009 - Am Vet Med Assoc

... d. Rimadyl injectable, 50 mg/mL, Pfizer Animal Health, Exton, Pa. e. IITC model 600 incapacitance meterIITC Life Science, Woodland, Calif. f. Canon Optura 40, Canon USA Inc, Lake Success, NY. g. Saint Louis Zoo Endocrinology Lab, Saint Louis Zoo, St Louis, Mo. ...

 

Analgesic effects of intramuscular administration of meloxicam in Hispaniolan parrots (Amazona ventralis) with experimentally induced arthritis

GA Cole, J Paul-Murphy… - American journal of …, 2009 - Am Vet Med Assoc

... d. 0.9% sodium chloride injection, USP, Hospira, Lake Forest, Ill. e. IITC Incapacitance Meter, model 600IITC Life Science, Woodland Hills, Calif. f. 24A-D Series parallel Shaft DC Gearmoter, model 0194, serial No. 0194JTE0015, Bodine Electric Co, Chicago, Ill. ...

 

[PDF] Kinematic and dynamic gait compensations resulting from knee instability in a rat model of osteoarthritis

KD Allen, BA Mata, MA Gabr, JL Huebner… - Arthritis Res …, 2012 - biomedcentral.com

... weight distribution was measured on an incapacitance meter (IITC, Inc., Woodland Hills, CA, USA), a behavioral analysis assay that measures weight bearing on the hindlimbs while the animal is in an induced rear- ing posture [10]. In brief, an incapacitance meter con- sists of ...

 

Single intrathecal administration of the transcription factor decoy AYX1 prevents acute and chronic pain after incisional, inflammatory, or neuropathic injury

J Mamet, M Klukinov, TL Yaksh, SA Malkmus… - PAIN®, 2014 - Elsevier

... In the SNI and the knee surgery models, incapacitance was measured as the difference in static weight bearing between the ipsilateral versus contralateral hind paw relative to the injury using an incapacitance meter (model 600IITC Life Science, Woodland Hills, CA). ...

 

[PDF] Efficacy of an equine joint supplement, and the synergistic effect of its active ingredients (chelated trace minerals and natural eggshell membrane), as

KJ Wedekind, A Josie, J Zhao - 2015 - dovepress.com

... A Hamilton PB 600-1 repeating dispenser (model 750; Hamilton Company, Reno, NV, USA) with a 700 series luer tip microliter syringe was used for precise injection ... An incapacitance tester (IITC Life Science, Woodland Hills, CA, USA) was used to measure weight distribution. ...

 

[HTML] Behavioral, medical imaging and histopathological features of a new rat model of bone cancer pain

L Doré-Savard, V Otis, K Belleville, M Lemire… - PLoS One, 2010 - dx.plos.org

... Static weight bearing was measured using the Incapacitance Meter (IITC Life Science, Woodland Hills, CA, USA). ... The results obtained with the incapacitance meter were used as a control for a second ... A 600-µl bolus of contrast agent (Gd-DPTA, Magnevist, Berlex) was injected ...

 

 

 

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