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疼痛与炎症研究

冷热板仪

时间:2016-09-21来源:本站作者:玉研仪器

详细介绍

冷热板痛觉测痛仪(大小鼠冷热板测试,冷热板,Hot Cold Plate Analgesia Meter for Mice and Rats测量动物对镇痛药物的疼痛反应极限同时进行冷热痛觉测试,更多详情敬请来电咨询)

 

传统的热板测试只能测试动物疼痛反应时间,同时由于冷却时间长不能用于温度升高测试和重复测试。PE34采用微处理器控制温度升高和降低,可以进行冷痛觉测试和热痛觉测试,用于测量动物对镇痛药物的疼痛反应极限,扩大了镇痛药物研究的范围。

 

冷热板痛觉测试仪主要特点:

 

Ø 快速升温和降温,每分钟可升降10℃,适合重复测试 温度稳定性为0.1℃

Ø 温度范围从0到70℃

Ø 时间精度为0.01秒

Ø 冷热板大小:4” x 8”

Ø 标准计算机打印口,输出 RS-232输出


Hot Cold Plate is used to measure the nociceptive threshold of analgesic compounds in mice and rats.

Conventional constant temperature hot plate tests only measure latencies of stronger narcotic agents.


Hot/Cold Plate Analgesia Meter widens the range of analgesia research to new levels. The unit is

microprocessor controlled and can be used for both incremental heating and cooling from any starting

temperature from 0 deg. c. to 70 deg. c in 0.1 degrees c. increments. The microprocessor monitors and

controls the rate of heating/cooling which can be set from 1 to 10 deg c. per minute. The front panel

display shows all test results including length of test in .01 sec. increments, starting temperature and

stopping temperature. The plate is uniformly heated/cooled at an adjustable rate and has automatic

upper/lower cut-off limits. All parameters are entered via front panel keypad. i.e. rate of temperature

increase/decrease, maximum/minimum temperature, date/time and animal number.



相关文献:

[HTML] Cell cycle inhibition limits development and maintenance of neuropathic pain following spinal cord injury

J Wu, Z Zhao, X Zhu, CL Renn, SG Dorsey, AI Faden - Pain, 2016 - ncbi.nlm.nih.gov

… Hot and cold plate tests were used to assess the thermal hyperesthesia [8]. An incremental
hot/cold plate (PE34; IITC Life Sciences, Woodland Hills, CA) with a starting temperature of
30°C and the hot and cold ramps, set at the maximum rate of 10 °C/min, was used to induce …


Transient receptor potential vanilloid 1 mediates nerve growth factorinduced bladder hyperactivity and noxious input

B Frias, A Charrua, A Avelino, MC Michel… - BJU …, 2012 - Wiley Online Library

… for 5 min. Latencies were determined before and 4 h after each NGF injection. For
that, animals were placed on the hot-plate apparatus (Series 8, model PE34, IITC
Life Sciences, Woodland Hills, CA, USA). The platform was …


HTMLVoluntary exercise training: analysis of mice in uninjured, inflammatory, and nerve-injured pain states

TD SheahanBA Copits, JP Golden, RW Gereau IV - PloS one, 2015 - journals.plos.org

… Values from both paws were averaged to determine withdrawal latency. Hot plate.
Prior to testing day, animals were individually acclimated to the hot plate chamber
(Model PE34 Series 8, IITC Life Science Inc.) for 15 min. On …


[HTML] Evaluation of antinociceptive effect of methanolic leaf and root extracts of Clitoria ternatea Linn. in rats

L Kamilla, S Ramanathan, S Sasidharan… - Indian journal of …, 2014 - ncbi.nlm.nih.gov

… The hot plate test was used as previously described.[9] The heated surface of a hot plate analgesia
meter (model PE34, series 3, IITC Life Science Series, Woodland hills, USA) was maintained at
55 ± 1°C. Each animal was placed on the heated surface of the plate …


[PDF] Analgesic and antioxidant properties of ethanolic extract of Terminalia catappa L. leaves

HV AnnegowdaMN Mordi, S Ramanathan… - International journal of …, 2010 - academia.edu

… Rats were placed on the heated surface of a hot plate analgesia meter (IITC Life Science Series
8, Model PE34, Victory Blvd, Woodland Hills, CA 91367, USA) maintained at 55+0.2°C. The time
taken for licking, shaking of forepaws or jumping was recorded as the index of …


HV Annegowda, MN Mordi, S. Ramanathan and SM Mansor

ISI Thomson - International Journal of Pharmacology, 2010 - scialert.net

… Rats were placed on the heated surface of a hot plate analgesia meter (IITC Life Science Series
8, Model PE34, Victory Blvd, Woodland Hills, CA 91367, USA) maintained at 55±0.2°C. The time
taken for licking, shaking of forepaws or jumping was recorded as the index of …


[HTML] Modality-specific peripheral antinociceptive effects of μ-opioid agonists on heat and mechanical stimuli: Contribution of sigma-1 receptors

Á Montilla-García, G Perazzoli, MÁ Tejada… - …, 2018 - Elsevier

… Then the plantar side of the stimulated hindpaw was placed on the surface of a thermal
analgesiometer (Model PE34, Series 8, IITC Life Science Inc., Los Angeles, USA) previously
set at 55 ± 1 °C until the animal showed a paw withdrawal response …

 



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