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当前位置:首页 > 给药·采样·染毒 > 明胶胶囊,装药器,投药器
给药·采样·染毒

明胶胶囊,装药器,投药器

时间:2016-12-01来源:本站作者:玉研仪器

详细介绍

明胶给药胶囊,非常适合用于对大鼠、小鼠进行胶囊式口部给药。

选择合适的型号,先对胶囊进行定量的药物灌装,再使用合适的工具将胶囊投入到胃内。



被验药物需要经口投药的情况下,使用胶囊会比其他方法来的更为合适与便利: 

粉末或者固体的药物,或者无法用导管进行投药的情况下,使用胶囊就可以轻松投药;
对应一些有臭味或者苦味的药剂,能够简单投药,减轻动物的痛苦;
个别制剂类药物的投药相当便利;
为了能够长时间持续的发挥药效,胶囊可以辅助充分吸收;
实验规程中必须要用胶囊进行投药的情况下,非常适合使用;
与药物混在饲料中进行喂食相比,用胶囊的方法更精准且无残留;

大号和小号胶囊都有对应的装药器和投药器可供选择,让装药和投药操作能够轻松完成;


玉研仪器公司可以提供国产订制型胶囊:胃溶、肠溶、结肠溶三种款式的大小鼠灌胃胶囊,一共六种型号:

大号胃溶胶囊,小胃溶胶囊

肠溶胶囊,小肠溶胶囊

结肠溶胶囊,小结肠溶胶囊


进口胶囊,只有胃溶性的款式,根据胶囊的外形尺寸,有多种规格可供选择:

根据需要,实验室可以自备胶囊包裹材料,自制成肠溶胶囊或结肠溶胶囊来使用,欢迎来电咨询。


Dosing Kits include capsules, funnel, stand, tamper, dosing device & instructional video


  • Ideal for materials that are insoluble, form poor suspensions, are affected by excipients or are odorous and distasteful, e.g., sustained release beadlets, paint flakes, chromic oxide marker
  • For capsule size, species, weight, and lower GI drug delivery size see table below. Capsule holders available for dip coating in enteric solutions. Capsule sinkers available for testing in disintegration test apparatus.
  • Size 9 can be used for intra-colonic delivery via rectal insertion in rats >200-250gm.
  • Save time and money by eliminating validation of suspension / solution homogeneity.
  • Eliminate excipients absorption affects.
 

Fill Materials:

Dry materials in any form
(powder, beadlets, crystals,
paint flakes), pastes, and
non-aqueous liquids.

Disintegration Time:

Within 10 minutes in stomach.

Dosing Time & Acceptance:
< 1 min. (30 - 45 minutes for 60 rats).  
> 98% successful dosing after minimal experience (3 - 4 placebo doses per rat).


on sizes 9el, 9 and 9h.
   

Animal Weight:

See below

Lower GI Drug Delivery:

See below

 
 
 Parameter Size 9el Size 9 Size 9h Size M
 Species & Weight Rats 200g+ Rats 200g 
(min 150g)
Guinea Pig 300g+
Hamsters & Rats 150g+ Mice 25g+
 Species & Weight Lower GI Delivery n/a Rat 200g+
Guinea Pig 300g+
Hamster 
& Rat 150g+ 
Guinea Pig 300g+
Mice 30g+
 Capsule Body Capacity 0.08 ml 0.025 ml 0.013ml 0.004 ml
 Fill Weight (materials with density 1g/ml) 80 mg 25 mg 13mg 4 mg
 External Diameter Maximum 2.71 mm 2.71 mm 2.71 mm 1.27 mm
 Length When Locked Maximum 23.0 mm 8.4 mm 5.1mm 8.4 mm

 Surface area locked capsule in sq mm for enteric coating.

Not Applicable 68mm2 42 mm2 31mm2
 Weight Empty (Cap & Body) Average1 17 mg 10 mg 5mg ~2 mg
 Colors Available Clear & Opaque Clear & Opaque Clear & Opaque White
For a specific net fill weight tare the weight of each capsule body individually and then fill or use a pre-weighed amount of powder for each capsule.

Tip: Order syringes for each technician to speed dosing.


胶囊装药器、胶囊投药器 



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