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生理信号测量

光遗传学记录分析系统

时间:2016-09-18来源:本站作者:玉研仪器

详细介绍

光遗传学系统采用LED光,用于刺激大脑一个或多个特定区域的具有视蛋白的神经元。可以结合EEG/EMG系统同时记录睡眠或癫痫的活动状态。该系统和Pinnacle数据采集系统和软件兼容。
 
OPTOGENETIC SYSTEM is designed to optically stimulate opsin-modified neurons in one or more specific brain regions using LEDs. It can be integrated into Pinnacle’s EEG/EMG systems to simultaneously record sleep or seizure activity. The system is also compatible with all Pinnacle Data Acquisition systems and Sirenia® software.

 
1. The Optogenetic Interface Module (OGIM) provides precise timing and illumination control of the LED fiber probe.
2. Our 8401-HS data conditioning and acquisition system (DCAS) performs secondary amplification and filtering before sending data to Pinnacle’s Sirenia Acquisition software of collection via USB.
3. The low-torque commutator, which is mounted above the cage, allows for unencumbered freedom of movement.
4. Electrophysiological signals are amplified and filtered at the head of the animal using our headstages. The mouse headstage contains up to 2 connectors to optogenetic LED probes and connects to a headmount via a friction fit.
5. Prefabricated headmounts reduce surgery time and provide ready-to-insert EMG leads.
6. An optional, SYNCHRONIZED VIDEO SYSTEM is available.
 
 

LED FIBER PROBES

Pinnacle’s optogenetic stimulation is based on LEDs coupled to 200/250 µM fiber optic cable with a minimum light output of 60mW/mm². The LED fiber probes are implanted using a guide cannula and standard stereotaxic techniques. The LED fiber probe assembly plugs directly into a 2 mm electrical header on the headstage, removing any requirements for an optical commutator.

Custom LED fiber probes are available upon request.
 

SIRENIA SOFTWARE MODULES

Our optogenetic systems come with Pinnacle  basic acquisition and analysis software and is available for free on our website. Additionally, we offer packages that automate the sleep scoring and seizure identification processes. Unlock these powerful tools for rapid data analysis by upgrading to our Sirenia  Seizure Pro or Sirenia Sleep Pro software.
  
SIRENIA    SEIZURE PRO is an advanced analysis package that provides a platform for quickly identifying and analyzing user-defined seizure events over a given time period.  


  
SIRENIA SLEEP PRO reduces scoring time by automating the process with tools such as cluster scoring, threshold scoring, hypnograms, and spectral analysis.  

  
SIRENIA    X-Y TRACKING accurately detects and analyzes animal movement within a cage. Track locomotor behavior in real time or in previously recorded video data. Our software is compatible with tethered and wireless animals.

 

 

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