双臂型脑立体定位仪Instrument Stereotaxic Standard Lab结构紧凑坚固，可以增加各种动物适配器，电极固定器注射装置，颅钻等。进行各种动物脑位区定位，注射给药，电极引导固定等工作。大鼠双臂标准系列脑立体定位仪在两边都有3向定位的操作臂，第二条操作臂可以根据手的习惯适当的扭转，两个操作臂在进行双注射或是边刺激边记录的时候，就非常有必要了。

 

大小鼠通用型脑立体定位仪是在标准大鼠脑立体定位仪基础上，增加小鼠适配器，使一台定位仪，可以同时满足小鼠和大鼠的实验。

 

脑立体定位仪的主要特点：

· 操作灵活、简便，标配大鼠适配器

· 脑立体定位仪标尺是由激光雕刻，清晰易读，精确度为0.1mm

· 脑立体定位仪操作臂移动范围（上下，左右，前后）：三方向移动距离80mm

· 垂直方向可90度转动，并随时锁定位置

· 扩充能力很强，可增加操作臂，增加注射装置及颅钻等

· 可以根据需要增加不同的固定器，用于多种动物

 

脑立体定位仪具有以下优势：

· 标尺易读数

· 移动平滑

· 全方位调节

· 电生理操作方便

· 配件多样，可选配各种动物适配器，麻醉罩以及颅钻

 

大鼠脑定位仪的主要构造：

 

数显型双臂脑立体定位仪：

ITEM	DESCRIPTION
51670	标准脑立体定位仪，配小鼠和大鼠适配器
51670E	Elliptic脑立体定位仪，底座旋转型，配小鼠和大鼠适配器
51670U	高精度标准脑立体定位仪，配小鼠和大鼠适配器
51673	双臂标准脑立体定位仪，配小鼠和大鼠适配器
51673E	Elliptic双臂脑立体定位仪，底座旋转型，配小鼠和大鼠适配器
51673U	高精度双臂标准脑立体定位仪，配小鼠和大鼠适配器

 

 

脑立体定位仪相关配件及可选配件：

大鼠门牙固定适配器	小鼠固定适配器
电极夹持器	电极、螺帽、注射器夹持器
电极、注射器夹持器	微量注射器
微量注射泵	颅骨钻

 小动物脑立体定位仪部分参考文献：
1. Albéri, L., Lintas, A., Kretz, R., Schwaller, B., & Villa, A. E. (2013). The calcium-binding protein parvalbumin modulates the firing 1 properties of the reticular thalamic nucleus bursting neurons. Journal of neurophysiology, 109(11), 2827-2841.
2. Sonati, T., Reimann, R. R., Falsig, J., Baral, P. K., O’Connor, T., Hornemann, S., Aguzzi, A. (2013). The toxicity of antiprion antibodies is mediated by the flexible tail of the prion protein. Nature, 501(7465), 102-106.
3. Ali, I., O’Brien, P., Kumar, G., Zheng, T., Jones, N. C., Pinault, D., O’Brien, T. J. (2013). Enduring Effects of Early Life Stress on Firing Patterns of Hippocampal and Thalamocortical Neurons in Rats: Implications for Limbic Epilepsy. PLOS ONE, 8(6), e66962.
4. Bell, L. A., Bell, K. A., & McQuiston, A. R. (2013). Synaptic Muscarinic Response Types in Hippocampal CA1 Interneurons Depend on Different Levels of Presynaptic Activity and Different Muscarinic Receptor Subtypes. Neuropharmacology.
5. Bolzoni, F., Bączyk, M., & Jankowska, E. (2013). Subcortical effects of transcranial direct current stimulation (tDCS) in the rat. The Journal of Physiology.
6. Bolzoni, F., Bączyk, M., & Jankowska, E. (2013). Subcortical effects of transcranial direct current stimulation (tDCS) in the rat. The Journal of Physiology.
7. Babaei, P., Tehrani, B. S., & Alizadeh, A. (2013). Effect of BDNF and adipose derived stem cells transplantation on cognitive deficit in Alzheimer model of rats. Journal of Behavioral and Brain Science, 3, 156-161.
8. Gilmartin, M. R., Miyawaki, H., Helmstetter, F. J., & Diba, K. (2013). Prefrontal Activity Links Nonoverlapping Events in Memory. The Journal of Neuroscience, 33(26), 10910-10914.
9. Feng, L., Sametsky, E. A., Gusev, A. G., & Uteshev, V. V. (2012). Responsiveness to nicotine of neurons of the caudal nucleus of the solitary tract correlates with the neuronal projection target. Journal of Neurophysiology, 108(7), 1884-1894.
10. Clarner, T., Diederichs, F., Berger, K., Denecke, B., Gan, L., Van der Valk, P., Kipp, M. (2012). Myelin debris regulates inflammatory responses in an experimental demyelination animal model and multiple sclerosis lesions. Glia, 60(10), 1468-1480.
11. Girardet, C., Bonnet, M. S., Jdir, R., Sadoud, M., Thirion, S., Tardivel, C., Troadec, J. D. (2011). Central inflammation and sickness-like behavior induced by the food contaminant deoxynivalenol: A PGE2-independent mechanism.Toxicological Sciences, 124(1), 179-191.
12. Hruška-Plocháň, M., Juhas, S., Juhasova, J., Galik, J., Miyanohara, A., Marsala, M., Motlik, J. (2010). A27 Expression of the human mutant huntingtin in minipig striatum induced formation of EM48+ inclusions in the neuronal nuclei, cytoplasm and processes. Journal of Neurology, Neurosurgery & Psychiatry, 81(Suppl 1), A9-A9.
13. Brooks, S., Jones, L., & Dunnett, S. B. (2010). A29 Frontostriatal pathology in the (C57BL/6J) YAC128 mouse uncovered by the operant delayed alternation task. Journal of Neurology, Neurosurgery & Psychiatry, 81(Suppl 1), A9-A10.
14. Yu, L., Metzger, S., Clemens, L. E., Ehrismann, J., Ott, T., Gu, X., Nguyen, H. P. (2010). A28 Accumulation and aggregation of human mutant huntingtin and neuron atrophy in BAC-HD transgenic rat. Journal of Neurology, Neurosurgery & Psychiatry, 81(Suppl 1), A9-A9.
15. Baxa, M., Juhas, S., Pavlok, A., Vodicka, P., Juhasova, J., Hruška-Plocháň, M., Motlik, J. (2010). A26 Transgenic miniature pig as an animal model for Huntington’s disease. Journal of Neurology, Neurosurgery & Psychiatry, 81(Suppl 1), A8-A9.

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